Table 7.
F-statistics and p-values for all main effects and interactions are shown for microglia and gene expression analysis.
| HIV-1 genotype | Stress | Stress × HIV-1 genotype | |
|---|---|---|---|
| Microglial branches (4A) | *F(1,8) = 14.62, p < 0.01 | F(1,8) = 2.17, p > 0.05 | F(1,8) = 2.38, p > 0.05 |
| Microglial junctions (4B) | *F(1,8) = 13.94, p < 0.01 | F(1,8) = 2.98, p > 0.05 | F(1,8) = 2.59, p > 0.05 |
| Microglial max branch length (4C) | *F(1,8) = 14.31, p < 0.01 | F(1,8) = 0.29, p > 0.05 | F(1,8) = 0.02, p > 0.05 |
| Average branch length (4D) | F(1,8) = 1.45, p > 0.05 | F(1,8) = 0.97, p > 0.05 | F(1,8) = 1.32, p > 0.05 |
| Lcn2 hippocampus (4A) | t15 = 1.18, p > 0.05 | ||
| Lcn2 PFC (4A) | *t15 = 2.40, p = 0.03 | ||
| Cfb (4B) | *t19 = 2.87, p = 0.01 | ||
| IBA-1-estimated population (Table 5) | F(1,8) = 0.32, p > 0.05 | F(1,8) = 3.26, p > 0.05 | F(1,8) = 0.54, p > 0.05 |
A two-way ANOVA was used for microglial morphology analysis (between-factors HIV-1 genotype and stress). A student’s t-test was used to assess significance of gene expression data. *Indicates a significant main effect or interaction. Blank boxes indicate an absence of a particular factor from analysis. The figure or table number is included in parentheses following the description of each metric. α = 0.05.