Figure 4. TNF-α but not mechanical stretch induced F-actin changes in human AF cells.
Immunocytochemistry for F-actin and vinculin in human AF cells seeded at 100,000 cells/mL immediately after 24 hours of stretch with and without TNF-α. F-actin and vinculin staining exhibited no apparent differences in cytoskeletal organization across all strain magnitudes. TNF-α treatment increased F-actin staining intensity but there were no discernable differences between strains in cytoskeletal structure with TNF- α treatment. (Magnification = 20X, Scale = 100 µm).
