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Effect of forskolin on TGF-β IR. (A, B) TGF-β1 IR in the cortex of 5-month-old APP/PS1 transgenic mice. After 10 days of forskolin treatment, TGF-β1 IR was reduced in cortex of treated (B) versus control (A) mice. (C) There was a significant reduction in area of TGF-β1 IR following 10 days of forskolin treatment (n = 6/group). **p < 0.01.
