Table 3.
Unadjusted and adjusted correlations between demographic and clinical characteristics and Change in SF-36 Physical Component Summary scores from 1 year to 2 years post-diagnosis (N=284)
| Change in SF-36 Physical Component Summary Score
|
||||||
|---|---|---|---|---|---|---|
| Variable | Na | Univariate Mean/β-estimate, ± SE | P-value/P for trend | Multivariateb Mean/β-estimate ± SE | P-value/P for trend | |
| Age at Diagnosis | 0.3090 | |||||
| Less than 55 years | 150 | -1.86 ± 0.74 | - | |||
| 55 years or greater | 134 | -0.77 ± 0.78 | - | |||
| Race/Ethnicity | 0.0701 | |||||
| Non-Hispanic White | 261 | -1.64 ±0.56 | - | |||
| Other | 23 | 1.93 ±1.88 | - | |||
| Education | 0.9406 | |||||
| Some High School (Grade9-12) | 20 | -1.71 ± 2.04 | - | |||
| High School Diploma or GED | 86 | -0.65 ± 0.98 | - | |||
| Vocational School or Some College | 119 | -1.84 ± 0.84 | - | |||
| Professional or Graduate School Experience | 55 | -1.14 ± 1.23 | - | |||
| Marital Status | 0.0014 | |||||
| Married or Living as Married | 191 | -2.55 ± 0.65 | - | |||
| Single/Divorced/Separated or Widowed | 92 | 1.10 ± 0.93 | - | |||
| Health Insurance | 0.8965 | |||||
| Have Insurance | 276 | -1.43 ± 0.54 | - | |||
| Do not have Insurance | 6 | -1.92 ± 3.68 | - | |||
| Household Income | 0.0843 | |||||
| $19,999 or Less | 31 | 1.33 ±1.67 | - | |||
| $20,000-$39,999 | 65 | -1.27 ±1.15 | - | |||
| $40,000-$74,999 | 81 | -1.77 ±1.03 | - | |||
| $75,000 or More | 63 | -2.15 ±1.17 | - | |||
| Employment Status | ||||||
| Paid Employment | 143 | -0.85 ±0.74 | - | |||
| No Paid Employment | 19 | -4.91 ±2.03 | 0.0619c | - | ||
| On leave or Unemployed because of Disability | 25 | 0.56 ±1.78 | 0.4618c | - | ||
| Retired or Homemaker | 82 | -1.46 ±0.98 | 0.6197c | - | ||
| Cancer Stage (SEER Stage) | 0.4172 | |||||
| Localized | 84 | -0.93 ± 1.00 | - | |||
| Regional | 62 | -0.83 ± 1.16 | - | |||
| Distant | 131 | -1.97 ± 0.80 | - | |||
| Disease Recurrence between 1 and 2 years post-diagnosis | <0.0001 | 0.0003 | ||||
| Recurred | 74 | -6.19 ± 1.04 | -4.33 ± 0.86 | |||
| Did not recur | 167 | 0.50 ± 0.68 | -0.46 ± 0.57 | |||
| Received chemotherapy between diagnosis and 1 year post-diagnosis | 0.9944 | |||||
| Did not receive | 18 | -1.42 ± 2.14 | - | |||
| Received | 260 | -1.40 ± 0.56 | - | |||
| Received radiation between diagnosis and 1 year post-diagnosis | 0.5773 | |||||
| Did not receive | 220 | -1.56 ± 0.61 | - | |||
| Received | 58 | -0.81 ± 1.19 | - | |||
| Received treatment between 1 to 2 years post-diagnosis | <0.0001 | |||||
| Did not receive | 166 | 0.66 ± 0.68 | - | |||
| Received | 118 | -4.17 ± 0.81 | - | |||
| Comorbid Conditions | 0.0911 | |||||
| None | 169 | -1.55 ± 0.69 | - | |||
| One | 66 | -2.53 ± 1.11 | - | |||
| Two or more | 48 | 0.95 ± 1.30 | - | |||
| Change in Comorbid conditions from 1 to 2 years post-diagnosis | 283 | -0.44 ± 0.76d | 0.5620 | - | ||
| Mental Health Conditions | 0.4758 | |||||
| Depression/Anxiety/Other Mental Health Issue | 25 | -2.58 ± 1.81 | - | |||
| None | 258 | -1.22 ± 0.56 | - | |||
| RSCL-M at 1 year Post-Diagnosis | 0.0062 | <0.0001 | ||||
| 30 ≤ Score ≤ 37 | 81 | -2.97 ±0.99 | 0.27 ± 0.99 | |||
| 37 < Score ≤ 43 | 66 | -1.71 ±1.10 | -0.85 ± 0.96 | |||
| 43 < Score ≤ 51 | 74 | -1.22 ±1.04 | -4.26 ± 0.91 | |||
| 51 < Score ≤ 88 | 54 | 1.41 ±1.21 | -4.77 ± 1.20 | |||
| Change in RSCL-M from 1 to 2 years post-diagnosis | 275 | -0.55 ±0.06e | <0.0001 | -0.54 ± 0.06d | <0.0001 | |
Abbreviations: RSCL-M, Modified Rotterdam Symptom Checklist; SE, Standard Error
May not sum to 284 due to missing covariate data
Multivariate model includes: recurrence between 1 to 2 years post-diagnosis, RSCL-M at 1 year post-diagnosis, change in RSCL-M between 1 to 2 years post-diagnosis and SF-36 physical component score at 1 year post-diagnosis
P-value for the category compared to Paid employment
β Estimate for change in number of comorbid conditions reported from 1 to 2 years post-diagnosis
β Estimate for change in symptom burden from 1 to 2 years post-diagnosis