FIG. 3.

MicroCT analysis of sheep lumbar vertebrae. (A) Representative microCT axial and sagittal reconstructions of sheep vertebrae treated with control, rhNELL-1 (0.9 mg) and rhNELL-1 (2.25 mg)-based implantation. After 3 months, microCT analysis was performed, including (B) BMD, (C) percentage bone volume (BV/TV), (D–F) trabecular bone measurements including, (D) Trabecular Thickness (Tb. Th), (E) Trabecular Number (Tb. N), and (F) Trabecular Spacing (Tb. Sp). n = 3 lumbar vertebrae per dose rhNELL-1, n = 6 control-treated lumbar vertebrae. n = 6 sheep in total. *p < 0.05, **p < 0.01 in comparison to control. Color images available online at www.liebertpub.com/tea