Table 1.
Patient Baseline Characteristics and Thyroid Hormone Doses
| Participant number | Sex | Age (years) | Race/ethnicity | Etiology of hypothyroidism | Patient weight (kg) | Serum TSH while taking LT4 (mIU/L) | LT4 dose (μg) | Weight-based LT4 dose (μg/kg) | Final LT3 dose (μg) |
|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 25 | Hisp | Hashimoto's | 81.9 | 0.8 | 137 | 1.67 | 30 |
| 2 | F | 24 | Caus | Hashimoto's | 65 | 0.9 | 88 | 1.35 | 30 |
| 3 | F | 35 | Asian | Hashimoto's | 55.5 | 2.4 | 75 | 1.35 | 30 |
| 4 | M | 43 | Caus | Hashimoto's | 94.7 | 1.7 | 75 | 0.79 | 30 |
| 5 | F | 24 | Caus | Hashimoto's | 68.3 | 2.67 | 75 | 1.09 | 30 |
| 6 | F | 45 | Caus | Hashimoto's | 81 | 2.7 | 100 | 1.23 | 45 |
| 7 | F | 56 | AA | Hashimoto's | 66.5 | 1.8 | 112 | 1.68 | 45 |
| 8 | F | 31 | Caus | Hashimoto's | 79.6 | 1.2 | 100 | 1.25 | 45 |
| 9 | F | 40 | Caus | Hashimoto's | 78.9 | 0.8 | 137 | 1.73 | 45 |
| 10 | F | 41 | Caus | Hashimoto's | 69.2 | 0.98 | 75 | 1.08 | 30 |
| 11 | F | 32 | AA | Hashimoto's | 131.2 | 1.56 | 75 | 0.57 | 30 |
| 12 | F | 24 | Caus | Hashimoto's | 100.2 | 1.49 | 100 | 0.99 | 45 |
| 13 | F | 35 | Caus | Hashimoto's | 88.3 | 3.28 | 75 | 0.85 | 30 |
| 14 | F | 47 | Caus | Hashimoto's | 119 | 1.29 | 175 | 1.47 | 45 |
| 15 | F | 47 | Caus | Hashimoto's | 52.8 | 0.4 | 100 | 1.89 | 45 |
| 16 | M | 50 | AA | Thyroidectomy | 96.9 | 2.19 | 150 | 1.55 | 60 |
| 17 | F | 50 | Caus | Hashimoto's | 68.3 | 1.11 | 75 | 1.09 | 30 |
| 18 | F | 36 | Caus | Hashimoto's | 74.5 | 0.97 | 112 | 1.50 | 45 |
TSH, thyrotropin; LT4, levothyroxine; LT3, liothyronine; F, female; M, male; Hisp, Hispanic; Caus, Caucasian; AA, African American.