Table 3.
Predictive factors for long-term survival by univariate and multivariate analysis in the NACT group
| n | Log-rank test χ2 value | P-value univariate | P-value multivariate | |
|---|---|---|---|---|
| Age (years) | ||||
| <55 | 20 | 1.471 | 0.225 | 0.058 |
| ≥55 | 36 | |||
| Differentiation | ||||
| Well/moderately | 20 | 0.803 | 0.370 | 0.796 |
| Poorly | 36 | |||
| Invasion depth | ||||
| T2 | 16 | 3.424 | 0.064 | 0.162 |
| T3/T4 | 40 | |||
| TNM stage | ||||
| II | 24 | 4.330 | 0.037 | 0.137 |
| III + IV | 32 | |||
| Lymph node metastasis | ||||
| No | 28 | 2.546 | 0.111 | 0.038 |
| Yes | 28 | |||
| FOXP3+ Tregs | ||||
| High | 19 | 9.825 | 0.002 | 0.652 |
| Low | 37 | |||
| GARP+ Tregs | ||||
| High | 20 | 14.610 | 0.000 | 0.013 |
| Low | 36 |
Notes: T2, tumor invasion of muscularis propria; T3, tumor invasion of subserosal connective tissue; T4, tumor invasion of serosal or adjacent structures; well/moderately, well/moderately differentiated carcinoma; poorly, poorly differentiated carcinoma.
Abbreviations: NACT, neoadjuvant chemotherapy; TNM, tumor, node, metastasis; Tregs, regulatory T-cells.