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. 2015 Dec 17;30(1):36–50. doi: 10.1111/jvim.13801

Figure 1.

Figure 1

The contractile apparatus of a cardiomyocyte. Interaction of thin (actin) and thick (myosin) filaments is mediated by the troponin complex (troponin I, T, and C) in the presence of calcium. The majority of troponin is structurally bound to the actin filament and its associated protein tropomyosin. A small percentage is found free in the cytosol.