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. 2016 May 30;38(6):340–351. doi: 10.1111/pim.12322

Figure 1.

Figure 1

SMA 12b decreases total cell counts and influx of eosinophils into the lungs of mice undergoing HDM‐induced airway inflammation. C57BL/6 mice undergoing HDM‐induced airway inflammation were treated with SMA 11a or 12b 1 h before administering HDM extracts throughout the model. The numbers after each SMA refer to the quantity of μg of SMA per injection. (a) structures of SMAs 11a and 12b. (b) total cell count in BALF collected at sacrifice. Influx of eosinophils and macrophages is shown as both total number of cells (c, e) and their proportion (d, f) in BALF, as determined by differential cell counts. Data are combined from 5 independent experiments. Symbols on each graph are representative of individual mice in the indicated groups and where *P < 0·05 and **P < 0·01 for 12b‐1‐versus HDM (none) mice and ###P < 0·001 for control vs. HDM mice.