. Author manuscript; available in PMC: 2016 Jun 20.

Published in final edited form as: Clin Cancer Res. 2013 Aug 21;19(20):5788–5797. doi: 10.1158/1078-0432.CCR-13-1217

Table 2. Association between PFS and methylation of VEGFA, VEGFB and VEGFC.

	TCGA cohort (HumanMethylation27 beadchip)
Genes	Genomic location	HR	95% CI	two-sided p value	N
VEGFA	chr6: 43845984-43845985	1.35	(0.99, 1.84)	0.056	311
VEGFB	chr11:63758874-63758875	1.95	(1.12,3.42)	0.018*	311
VEGFC	chr4: 177951450-177951451	0.92	(0.86, 0.99)	0.021*	311

	SGCTG cohort (Bisulfite Pyrosequencing)
Genes	Genomic location	HR	95% CI	one-sided p value	N

VEGFA	chr6: 43845984-43845985	1.17	(0.94, 1.44)	0.08⁺	141
VEGFB	chr11: 63758262-63758287	1.12	(0.99, 1.28)	0.044*	126
VEGFC	chr4: 177951442-177951520	0.99	(0.98, 1.00)	0.03*	142