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. Author manuscript; available in PMC: 2016 Jun 20.
Published in final edited form as: Oncogene. 2013 Oct 14;33(37):4599–4612. doi: 10.1038/onc.2013.417

Figure 3. Inflammation in skin of pRbΔEpi;p21-/- mice.

Figure 3

A-F”’) Representative immunohistochemistry (A-C”’ and F-F”’) and immunofluorescence (D-D”’, F”’) images showing the presence of T cells (CD3ε positive) (A-A”’, F), macrophages (F480 positive) (B-B”’, F’), mastocytes (C-C”’, F”) and γδT cells (D-D”’, E”’) in pRbF/F (A, B, C, D), p21-/- (A’, B’, C’, D’) pRbΔEpi (A”, B”, C”, D”) and pRbΔEpi;p21-/- (A”’, B”’, C”’, D”’) mouse skin and pRbΔEpi;p21-/- skin grafts (F, F’, F”, F”’). Bars=100μm. E) Representative Western blots showing the expression of the specified proteins in newborn skin extracts of mice of the quoted genotype. Each lane contains a pool of extracts from 3 different mice of each genotype. The corresponding densitometric analysis of the different bands normalized according the corresponding Actin value is provided in Supp Fig S3.