Table 2. Summary of characteristics studies.

Author	Duration of studies (months)	No. NHD patients	Men (n)	Mean age (years)mean±SD	In-centre /home NHD	Duration of NHD treatment	Study design	Single centre y/n	Control group y/n	Meta analysisy/n	Study quality
Alloatti,2002	>6	13	12 (92.3%)	52.0±13.0	In-centre	3 times/week for 8 hours	prospective	Y	N	N	4
Cravedi,2009	24	7	6 (85.7%)	50.4±11.0	In-centre	3 times/week for 8 hours	retrospective	Y	N	Y	5
David,2009	12	13	11 (84.6%)	34.8±13.7	In-centre	3 times/week for 8 hours	prospectivelongitudinal	Y	N	Y	5
Demirci,2013	12	57	41 (71.9%)	47.1±11.7	In-centre	3 times/week for 8 hours	prospective cohort trial	N	Y	Y	7
Ipema,2012	8	15	11 (73.3%)	53.4±10.3	Home	5/6 times/week for 8 hours	prospective observational	Y	N	Y	5
Kaysen,2012	12	87	57 (65.5%)		Home		prospective randomized trial	N	Y	Y	8
		42	28 (66.7%)	54.0±12.9		3 times/week ≥ 2.5 hours
		45	29 (64.4%)	51.7±14.4		6 times/week ≥ 6 hours
Maduel,2011	12	26	18 (69.2%)	49.2±14.0	In-centre		crossover prospective	Y	N	N	8
McPhatter,1999	18	11	5 (45.5%)	50.0±na	Home	5–6 times/week for 4–9 hours	prospectiveobservational	Y	N	N	5
O’Sullivan, 1998	2	5	3 (60%)	46,6±na	In-centre	6 times/week for 8 hours	pilot study	Y	N	N	3
Pierratos,1997	36	11	8 (72.7%)	40±10.0	Home	6–7 times/week for 8–10 hours	prospective	Y	N	Y	5
Schorr,2011	6	12	6 (50%)	54,2±13.0	Home	5–6 times/week for≥ 6 hours	randomized trial	Y	Y	Y	7
Sikkes,2009	12	14	13 (92.9%)	47.0±7.8	Home	6 times/week for 8 hours	prospective non-randomized	Y	N	Y	5
Spanner,2003	18	13	10 (76.9%)	44,2±6.4	Home	5–6 times/week for 6–8 hours	prospective controlled non-randomized	N	Y	Y	7

Abbreviations: NHD: nocturnal hemodialysis.