Table 2.

Relationship of NK1R expression with clinicopathological features of CRC

Parameters	Strong expression	Weak or no expression	χ2	P-value
Age
<67 years	96	27	1.486	0.260
≥67 years	103	41
Sex
Male	112	30	3.012	0.092
Female	87	38
Distance metastasis
Yes	7	1	0.731	0.469
No	192	67
Lymph nodes metastasis
Positive	88	18	6.671	0.010
Negative	111	50
TNM stage
I + II	23	16	5.823	0.019
III + IV	176	52
Pathology grading
I	14	7	1.208	0.566
II	130	40
III	55	21

Abbreviations: NK1R, neurokinin-1 receptor; CRC, colorectal cancer; TNM, tumor node metastasis.