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. 2016 Jun 15;9:3535–3544. doi: 10.2147/OTT.S106351

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© 2016 Xiao et al. This work is published and licensed by Dove Medical Press Limited

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Overexpression of IGF-1R reverses miR-503-mediated suppressive effects on LM3 and HepG2 cells.

Notes: LM3 and HepG2 cells were transfected with miR-503 mimic with or without IGF-1R plasmid. (A) The protein levels of IGF-1R were then examined using Western blot assay. (B) MTT assay and (C) flow cytometry were conducted to examine the cell proliferation and apoptosis, respectively. **P<0.01 vs miR-503. ***P<0.001.

Abbreviations: miR, microRNA; IGF-1R, insulin-like growth factor 1 receptor; PI, pethidium bromide; UL, upper left; UR, upper right; LL, lower left; LR, lower right.