Table 2.

Association between miR-503 expression and clinicopathologic characteristics of patients with hepatocellular carcinoma

Variants	Low expression (n=47)		High expression (n=40)		P-value
	n	%	n	%
Age (years)					0.976
≤50	21	44.7	18	45
>50	26	55.3	22	55
Sex					0.996
Male	27	57.4	23	57.5
Female	20	42.6	17	42.5
Tumor number					0.989
Single	40	85.1	34	85
Multiple	7	14.9	6	15
Tumor size (cm)					0.838
≤5 cm	26	55.3	23	57.5
>5 cm	21	44.7	17	42.5
Histologic grade					0.004
High and moderate	28	59.6	35	87.5
Poor	19	40.4	5	12.5
Nodal metastasis					0.001
Present	26	55.3	8	20
Absent	21	44.7	32	80
Vascular invasion					0.004
Present	30	63.8	13	32.5
Absent	17	36.2	27	67.5
HBV infection					0.894
Present	42	89.4	37	92.5
Absent	5	10.6	3	7.5
Clinical stage					0.005
I–II	20	42.6	29	72.5
III–IV	27	57.4	11	17.5
AFP (ng/mL)					0.069
≤400	19	40.4	24	60
>400	28	59.6	16	40

Abbreviations: miR, microRNA; HBV, hepatitis B virus; AFP, alpha fetal protein.