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Excretion of Cu from Cu NPs and Cu ions.
Notes: Cu levels in (A) urine and (B) feces of Cu NP- and Cu ion-treated rats are measured at 0 hour (control), 12 hours, 24 hours, 48 hours, 72 hours, 1 week, 2 weeks, and 4 weeks after a single oral dose of 500 mg/kg each. Values are presented as mean ± SD (n=3). *P<0.05, **P<0.01 vs vehicle control. Cu ions, copper(II) chloride.
Abbreviations: Cu NPs, copper nanoparticles; SD, standard deviation.
