Table S2.
Absolute and relative organ weights in rats treated with Cu ions
| Items | Cu ions (mg/kg)
|
||||
|---|---|---|---|---|---|
| 0 | 156 | 312 | 625 | 1,250 | |
| Male | |||||
| Number of rats | 5 | 5 | 5 | 3 | – |
| Body weight at term | 412.6±6.01 | 404.9±13.11 | 382.3±8.26 | 382.3±30.63 | – |
| Brain (g) | 1.90±0.021 | 1.98±0.081 | 1.94±0.075 | 2.00±0.275 | – |
| Per bw (%) | 0.45±0.003 | 0.49±0.026 | 0.52±0.072 | 0.50±0.053 | – |
| Liver (g) | 14.94±0.731 | 14.36±1.015 | 13.44±0.668 | 14.92±3.057 | – |
| Per bw (%) | 3.61±0.232 | 3.54±0.212 | 3.61±0.102 | 3.69±0.332 | – |
| Spleen (g) | 0.86±0.042 | 0.82±0.037 | 0.80±0.071 | 0.89±0.110 | – |
| Per bw (%) | 0.21±0.016 | 0.20±0.024 | 0.21±0.017 | 0.22±0.022 | – |
| Heart (g) | 1.20±0.071 | 1.15±0.062 | 1.10±0.060 | 1.14±0.185 | – |
| Per bw (%) | 0.28±0.023 | 0.28±0.023 | 0.29±0.010 | 0.28±0.018 | – |
| Thymus (g) | 0.59±0.071 | 0.52±0.051 | 0.49±0.124 | 0.46±0.102 | – |
| Per bw (%) | 0.13±0.028 | 0.13±0.038 | 0.13±0.0305 | 0.12±0.0367 | – |
| Lung (g) | 1.51±0.163 | 1.48±0.083 | 1.46±0.044 | 1.59±0.127 | – |
| Per bw (%) | 0.35±0.026 | 0.37±0.026 | 0.39±0.014 | 0.40±0.064 | – |
| Kidneys (g) | 2.53±0.014 | 2.47±0.028 | 2.44±0.186 | 2.70±0.419 | – |
| Per bw (%) | 0.61±0.005 | 0.61±0.019 | 0.65±0.036 | 0.67±0.027** | – |
| Adrenal glands (g) | 0.048±0.0007 | 0.048±0.003 | 0.048±0.006 | 0.048±0.003 | – |
| Per bw (%) | 0.012±0.0013 | 0.012±0.001 | 0.013±0.002 | 0.012±0.002 | – |
| Testes (g) | 3.45±0.269 | 3.51±0.219 | 3.51±0.249 | 3.53±0.326 | – |
| Per bw (%) | 0.84±0.031 | 0.87±0.057 | 0.94±0.049 | 0.88±0.118 | – |
| Prostate (g) | 0.63±0.048 | 0.65±0.071 | 0.68±0.105 | 0.67±0.192 | – |
| Per bw (%) | 0.15±0.022 | 0.16±0.022 | 0.15±0.053 | 0.17±0.050 | – |
| Seminal vesicles (g) | 2.06±0.276 | 1.88±0.276 | 1.68±0.376 | 1.67±0.186 | – |
| Per bw (%) | 0.50±0.035 | 0.464±0.102 | 0.452±0.103 | 0.408±0.044 | – |
| Epididymides (g) | 1.06±0.092 | 1.07±0.048 | 1.08±0.015 | 1.01±0.132 | – |
| Per bw (%) | 0.26±0.011 | 0.26±0.013 | 0.26±0.010 | 0.25±0.028 | – |
| Female | |||||
| Number of rats | 5 | 5 | 4 | 3 | – |
| Body weight at term | 257.4±13.18 | 261.7±10.37 | 254.0±17.64 | 241.8±2.40 | – |
| Brain (g) | 1.69±0.064 | 1.78±0.078 | 1.80±0.132 | 1.75±0.127 | – |
| Per bw (%) | 0.72±0.032 | 0.68±0.024 | 0.71±0.004 | 0.72±0.060 | – |
| Liver (g) | 8.27±0.898 | 8.47±0.716 | 8.59±1.212 | 8.34±0.021 | – |
| Per bw (%) | 3.21±0.389 | 3.24±0.297 | 3.37±0.258 | 3.45±0.026 | – |
| Spleen (g) | 0.69±0.021 | 0.67±0.035 | 0.63±0.058 | 0.53±0.071** | – |
| Per bw (%) | 0.27±0.012 | 0.26±0.019 | 0.25±0.008 | 0.22±0.027** | – |
| Heart (g) | 0.78±0.078 | 0.81±0.056 | 0.84±0.062 | 0.82±0.042 | – |
| Per bw (%) | 0.30±0.034 | 0.31±0.027 | 0.33±0.012 | 0.34±0.021 | – |
| Thymus (g) | 0.35±0.021 | 0.37±0.098 | 0.43±0.121 | 0.38±0.035 | – |
| Per bw (%) | 0.15±0.010 | 0.14±0.033 | 0.17±0.045 | 0.20±0.017* | – |
| Lung (g) | 1.30±0.212 | 1.31±0.122 | 1.19±0.098 | 1.12±0.127 | – |
| Per bw (%) | 0.51±0.089 | 0.50±0.031 | 0.47±0.012 | 0.46±0.048 | – |
| Kidneys (g) | 1.61±0.071 | 1.68±0.074 | 1.53±0.060 | 1.80±0.163 | – |
| Per bw (%) | 0.63±0.035 | 0.64±0.046 | 0.60±0.044 | 0.74±0.075* | – |
| Adrenal glands (g) | 0.064±0.0190 | 0.067±0.0092 | 0.071±0.0054 | 0.060±0.0087 | – |
| Per bw (%) | 0.025±0.0071 | 0.026±0.0057 | 0.028±0.0041 | 0.025±0.0034 | – |
| Ovaries (g) | 0.099±0.0253 | 0.091±0.0178 | 0.085±0.0220 | 0.101±0.0148 | – |
| Per bw (%) | 0.038±0.0094 | 0.035±0.0081 | 0.033±0.0077 | 0.042±0.0064 | – |
Notes: Values are presented as mean ± SD. “–” indicates no record of organ weights.
*
P<0.05,
**
P<0.01 vs vehicle control.
Abbreviations: bw, body weight; SD, standard deviation.