Table 2.
Steady-state flux, apparent permeability coefficient (Papp), lag time, and regression coefficient of L-carnosine
| Formulation | Steady-state flux (µg/h) | Papp×10−6 (cm/s) | Lag time (min) | Regression coefficient (R2) |
|---|---|---|---|---|
| L-carnosine* | 390±32 | 9.0±0.2 | 20±4.2 | 0.995 |
| PC1:1 | 250±26 | 7.0±0.1 | 15±3.0 | 0.987 |
| PC1:2 | 200±15 | 4.5±0.1 | 10±2.8 | 0.996 |
| PC1:2 HA | 70±4.0 | 0.8±0.2 | 29±0.5 | 0.998 |
Note:
*
L-carnosine solution of 1% w/w was prepared in PBS.
Abbreviations: PC, phospholipid complexes; min, minutes; HA, hyaluronic acid; PBS, phosphate buffered saline.