Table 4.
Interfacial tension of internal phase and external phase and the calculated dewetting of ibuprofen crystal at different times of evaporation (n=3)
Time (hours) | Interfacial tension (γOW) (mN/m−1 ± SD) | Contact angle of internal phase on ibuprofen plate (θO) (° ± SD) | Dewetting value |
---|---|---|---|
8 | 8.41±0.13 | 20.46±0.79 | 7.88 |
16 | 7.94±0.04 | 22.65±1.20 | 7.32 |
24 | 7.80±0.08 | 30.71±1.31 | 6.71 |
32 | 7.45±0.10 | 36.03±1.16 | 6.03 |
40 | 6.87±0.10 | 40.31±1.54 | 5.24 |
48 | 6.40±0.09 | 41.35±1.52 | 4.80 |
Abbreviation: SD, standard deviation.