Table 5. Rate constants of the B- to Z-DNA transition of the (GC)7 hairpin structure calculated by fitting the CD kinetics curves to a mono-exponential function. The rate constants are an average of two independent measurements.
Sequence | k (10−3 s−1) | |
---|---|---|
4.5 M NaCl | 3 M NaCl | |
Unmodified hairpin | 5.75a | 2.2a |
D3 | 5.75a | - |
D3A8 | 7.8a | - |
D3A10 | 7.55a | - |
D3A12 | 5.6a | - |
aErrors are <10%.