Table 1. Overview of known and novel snoRNAs analyzed in this study.
| Known snoRNAs | Novel snoRNAs | ||||||
|---|---|---|---|---|---|---|---|
| Type of snoRNA | Total count | Currently recognized by the HGNC | Changes/Additions requested at the HGNC | Not sufficiently supported to be added to HGNC | Total count | Additions requested at the HGNC | Not sufficiently supported to be added to HGNC |
| H/ACA box | 179 | 136 | +39/-3 | 4 | 11 | 9 | 2 |
| AluACA | 348 | 0 | 0 | 348 | 6 | 0 | 6 |
| C/D box | 376 | 295 | 48 (+4) | 29 | 41 | 14 (+21) | 6 |
| C/D-box like | 18 | 0 | 0 (+8) | 10 | 98 | 0 (+98) | 0 |
| scaRNAs | 29 | 27 | 2 | 0 | 0 | 0 | 0 |
| Telomerase | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| sno-lnc RNAs | 11 | 0 | 0 | 11 | 0 | 0 | 0 |
‘Known snoRNAs’ are either annotated by the HGNC or extracted from recently published literature (24,33,39,64,72), and/or the public databases GENCODE and deepBase. ‘Novel snoRNAs’ are those genes that do not overlap any of the known ones, naturally. In brackets, we provide counts of putative snoRNAs that give at least rise to processed transcripts, but only partially fulfil our criteria for applying at the HNGC for gene names (new HGNC prefix pending).