Table 1. The most significant LDSS-P positive peaks corresponding to KEGG pathways.

			Motif position
KEGG ID	Pathway	Motif	from	to	Number of genes	Rep. factora
00010	Glycolysis / Gluconeogenesis	ARATCG	−89	−78	33	6.67
00030	Pentose phosphate pathway	GSCRCC	−88	−80	70	13.16
00040	Pentose and glucuronate interconversions	AASYGC	−55	−46	55	11.11
00051	Fructose and mannose metabolism	GCHATC	−9	2	48	10.71
00052	Galactose metabolism	GKCWAG	−24	−13	55	15.00
00061	Fatty acid biosynthesis	AWRCCA	−94	−83	29	14.29
00190	Oxidative phosphorylation	CDTGTT	−44	−36	34	4.94
00240	Pyrimidine metabolism	AAACBT	−101	−93	17	6.12
00250	Alanine, aspartate and glutamate metabolism	GCDTGC	−46	−34	64	9.30
00270	Cysteine and methionine metabolism	GACYSG	−39	−30	42	13.79
00290	Valine, leucine and isoleucine biosynthesis	TYCCKC	−83	−75	50	13.04
00330	Arginine and proline metabolism	TTGCSC	−77	−67	38	5.80
00480	Glutathione metabolism	CWTGYC	−47	−36	96	13.79
00500	Starch and sucrose metabolism	TRCGCG	−74	−65	33	10.00
00520	Amino sugar and nucleotide sugar metabolism	AAMARG	2	12	72	10.26
00620	Pyruvate metabolism	ARATCG	−89	−78	33	6.38
00680	Methane metabolism	TCAHCC	−101	−93	19	6.12
00710	Carbon fixation in photosynthetic organisms	CCKCCG	−72	−63	47	11.11
00770	Pantothenate and CoA biosynthesis	AVCGGA	1	12	55	12.00
00860	Porphyrin and chlorophyll metabolism	CWTRCA	−39	−33	44	7.89
00970	Aminoacyl-tRNA biosynthesis	CCKSAA	−99	−91	52	10.71
01200	Carbon metabolism	TCAHCC	−101	−93	19	2.78
01210	2-Oxocarboxylic acid metabolism	TYCCKC	−83	−75	50	9.09
01212	Fatty acid metabolism	AWRCCA	−94	−83	29	9.09
02010	ABC transporters	CKMTTG	−46	−38	117	2.06
02020	Two-component system	TTWAYC	−40	−27	66	6.96
02040	Flagellar assembly	TAACSA	−34	−26	22	9.68
03010	Ribosome	AWAMGC	−15	−7	46	9.09
03018	RNA degradation	GSKTGC	−81	−69	73	22.22
03030	DNA replication	CARSGG	−97	−86	53	25.00
03060	Protein export	TCRMTT	−51	−37	65	18.75
03070	Bacterial secretion system	TGGDAT	−59	−52	14	10.34
03430	Mismatch repair	CARSGG	−97	−86	53	13.64
04112	Cell cycle - Caulobacter	TTWAMC	−36	−27	45	10.00
05134	Legionellosis	TAACSA	−34	−26	22	20.00
M00001	Glycolysis (Embden-Meyerhof pathway)	THCCGC	−83	−75	39	18.75
M00003	Gluconeogenesis	THCCGC	−83	−75	39	27.27
M00004	Pentose phosphate cycle	CATHTT	−50	−41	33	17.65
M00048	Inosine monophosphate biosynthesis	GCHATC	−9	2	48	33.33
M00144	NADH: quinone oxidoreductase, prokaryotes	TCMKCT	−98	−91	24	10.71
M00178	Ribosome, bacteria	AWAMGC	−15	−7	46	9.09
M00237	Branched-chain amino acid transport system	TCMTKT	−43	−34	48	12.00
M00359	Aminoacyl-tRNA biosynthesis, eukaryotes	CCSTYG	−47	−38	85	16.67

^aRepresentation factor.