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. 2016 Mar 2;7(11):11945–11958. doi: 10.18632/oncotarget.7858

Figure 1. Effect of TNF-α blockade on the expression of miRs and their target proteins in LPS-exposed THP-1 cells.

Figure 1

A. TNF-α release into the culture medium by THP-1 cells after LPS treatment (1 μg/ml), expressed as pg/ml per 100,000 cells. B. MiR-146a-5p expression in THP-1 cells after 30 min or 5 h (hours) LPS exposure, with/without 24 h anti-TNF-α pretreatment, measured as fold change vs ctrl. C. MiR-126-3p expression in THP-1 cells after 30 min or 5 h LPS exposure, with/without 24 h anti-TNF-α pretreatment, measured as fold change vs ctrl. D. Irak1 and Spred1 expression levels and densitometry data in THP-1 cells after 30 min or 5 h LPS stimulation, with/without 24 h anti-TNF-α pretreatment. * Student's t test, p < 0.05. Data are mean ± S.D. of 3 independent experiments.

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