Skip to main content
. 2016 Feb 23;7(11):12063–12074. doi: 10.18632/oncotarget.7642

Figure 9. GDF11 decreases the phosphorylation level of eNOS (Ser1177) in HUVECs.

Figure 9

A. The time-course of eNOS expressions showed that GDF11 significantly reduced p-eNOS(Ser1177) expression in protein level after 48h treatment. **P < 0.01 vs. 0h. n = 10. B. Compared with parallel control, GDF11 reduced p-eNOS(Ser1177) expression in protein level after 48h treatment. **P < 0.01 vs. Control. n = 30. C. GDF11-induced decrease of p-eNOS(Ser1177) protein level was restored by antioxidant mitoTEMPO (25nM). The cells were pre-treated by mitoTEMPO for 1h and then GDF11(50ng/ml) was added.*P < 0.05 vs. control.## P < 0.01 vs. GDF11-treated group. n = 8.