Figure 3. Resveratrol represses the expression of fibrogenic proteins of fibrotic BMFs.
1×105 cells/well of fibrotic BMF cell lines were seeded into 6-well-plate and cultured with 0.5% FBS/DMEM at 37°C with 0, 25, 50, 100 μM resveratrol for 48 hours A., B. or with 100 μM resveratrol for 1 to 4 days C., D., E. Total proteins were extracted the expression of fibrogenic proteins were determined by western blot. The inserted numbers represented relative expression when compared with 0.1% ethanol treated group (A, B) or Day 0 group (C, D). The experiments were repeated for three times and data from a representative experiment were presented. *, p < 0.05; **, p < 0.01 as compared to the data from 0.1% ethanol treated group.