Figure 3. Circulating miR-21 expression reflects expression of miR-21 in tumour tissue.

Matched baseline plasma and Formalin-Fixed-Paraffin-Embedded tissues were analysed. Circulating miR-21 expression was quantitated by ddPCR, and tissue miR-21 expression was assessed by ISH. Patients with high circulating levels of miR-21 had tumours with high miR-21 expression in cancer cells in the tissues.