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. 2016 Feb 12;7(11):12904–12916. doi: 10.18632/oncotarget.7354

Figure 1. Multivariate modelling resulting from the analysis of serum 1H-NMR spectra.

Figure 1

OPLS-DA score plots for the comparisons between: A. healthy individuals (Inline graphic) vs. NSCLC patients (early-stage and advanced-stage, Inline graphic and Inline graphic, respectively); B. healthy individuals (Inline graphic) vs. early-stage NSCLC patients (Inline graphic); C. healthy individuals (Inline graphic) vs. advanced-stage NSCLC patients (Inline graphic) and D. early-stage NSCLC patients (Inline graphic) vs. advanced-stage NSCLC patients (Inline graphic). SUS-plots derived from the OPLS-DA models between: E. healthy individuals vs. early-stage NSCLC patients (model B, horizontal axis) and healthy individuals vs. advanced-stage NSCLC patients (model C, vertical axis); F. healthy individuals vs. NSCLC patients (model A, horizontal axis) and early-stage NSCLC vs. advanced-stage NSCLC patients (model D, vertical axis). Rectangles indicate unique biomarkers for each model.