Skip to main content
. 2016 Feb 21;7(11):13139–13152. doi: 10.18632/oncotarget.7545

Figure 2. Overexpression of miR-194 suppresses NSCLC cell proliferation.

Figure 2

(A) Overxpression of miR-194 in H1299 and A549 cells transfected with the miR-194 vector with respect to cells transfected with the control vector was confirmed by qRT-PCR. (B) CCK-8 assays demonstrating the effect of miR-194 overexpression on the proliferation of H1299 and A549 NSCLC cells. (C) Colony formation assays demonstrating the effect of miR-194 overexpression on the proliferation of H1299 and A549 NSCLC cells. Error bars represent mean ± the standard deviation from three independent experiments. Representative colony formation images are also provided. (D) A photo of dissected tumors demonstrates the smaller size of tumors that were derived from A549 cells that overexpressed miR-194. (E-F) Tumor volume was measured weekly, and tumor weight was determined at day 35. **P < 0.01.