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. 2016 Feb 21;7(11):13139–13152. doi: 10.18632/oncotarget.7545

Figure 4. miR-194 inhibits the migratory, invasive, and metastatic capacities of NSCLC cells.

Figure 4

(A–B) Migration and invasion assays of H1299 and A549 NSCLC cells transfected with the control vector or the miR-194 vector. Representative micrographs demonstrating migrating and invasive cells are also provided. Average number of invasive or migratory cells per high power field from three independent experiments ± the standard deviation is shown at the right. (C) Mice injected with A549 cells transfected with the miR- 194 vector had significantly fewer pulmonary metastases than control. Representative histologic section from the dissected lungs of the mice are also provided. Magnification: ×100 (left), ×200 (right). **P < 0.01.