Table 3. Summary of efficacy endpoints - 5 years by treatment from diagnosis.
| All patients (n = 236) |
NCT (n = 98) | NCAT (n = 138) | Hazard Ratio | p | |
|---|---|---|---|---|---|
| 5-Year Overall Survival | 77.4% (70.2, 83.1) | 83.3% (66.2, 92.2) | 74.0% (65.0, 81.1) | 0.70 (0.34, 1.44) | 0.336 |
| 5-Year Event-free Survival | 63.7% (55.8, 70.5) | 69.6% (51.5, 82.0) | 59.3% (49.8, 67.6) | 0.63 (0.37, 1.08) | 0.091 |
| 5-Year Breast Cancer Specific Survival | 80.3% (73.7, 86.1) | 84.8% (70.8, 94.4) | 77.9% (69.9, 85.0) | 0.72 (0.33, 1.56) | 0.408 |
| Odds Ratio | p | ||||
| Total pCR Rate (n = 230) | 19.6% (45) | 33.3% (31) | 10.2% (14) | 4.39 (2.18, 8.86) | <0.001 |
| Breast pCR Rate | 23.3% (55) | 38.8% (38) | 12.3% (17) | 4.51 (2.35, 8.64) | <0.001 |