. Author manuscript; available in PMC: 2016 Aug 2.

Published in final edited form as: Mol Psychiatry. 2016 Feb 2;21(7):956–968. doi: 10.1038/mp.2015.222

Table 1.

Maternal serum cytokine response profile following injection of Poly IC or Saline.

	Saline	1 mg/kg Poly IC	2.5 mg/kg Poly IC	5 mg/kg Poly IC
IL-6 (pg/mL)	25±6	20405±4299	36430±4066^***	155828±51107^***
TNFα (pg/mL)	16±0	77±43	151±64	485±187^**

Levels of interleukin-6 (IL-6) and tumor necrosis factor alpha (TNFα) were analyzed from serum collected from pregnant mothers 3 hours following an injection of 1, 2.5 or 5 mg/kg Poly IC or Saline on embryonic day 9. Poly IC dose-dependently increased maternal serum levels of both IL-6 and TNFα. Data shown is mean±standard error of the mean. N-values for IL-6 experiment are Saline (7), 1 mg/kg Poly IC (6), 2.5 mg/kg Poly IC (7), 5 mg/kg Poly IC (6). N-values for TNFα experiment are Saline (4), 1 mg/kg Poly IC (3), 2.5 mg/kg Poly IC (3), 5 mg/kg Poly IC (3). Kruskill-Wallis test followed by Dunn's Multiple Comparison test.

^**

p<0.01

^***

p<0.001.