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Maternal and fetal outcomes following injection of Poly IC or Saline. Poly IC administered on embryonic day 9 dose-dependently increased maternal and fetal deaths.
| Treatment | Injected | Maternal Deaths |
Live Births |
% Live Births |
Surviving Pups |
Male Pups |
Female Pups |
Pups Lost |
Average Surviving Pups/Litter |
|---|---|---|---|---|---|---|---|---|---|
| Saline | 5 | 0 | 5 | 100 | 21 | 13 | 8 | 7 | 4 |
| 1 mg/kg Poly IC | 9 | 0 | 7 | 78 | 18 | 11 | 7 | 6 | 3 |
| 2.5 mg/kg Poly IC | 7 | 0 | 2 | 29 | 5 | 1 | 4 | 1 | 3 |
| 5 mg/kg Poly IC | 8 | 4 | 0 | 0 |
