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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Am J Prev Med. 2016 Mar 30;51(1):33–45. doi: 10.1016/j.amepre.2016.01.029

Table 2.

Chronic Conditions with the Lowest (≤20th percentile) and Highest (≥80th percentile) Incidence and Prevalence of Substance Use Behaviors

Pre-adolescence (<14 yrs) Adolescence (15–17 yrs) Transition (18–20 yrs) Early adulthood (21–23 yrs) Adulthood (24+yrs)
≤ 20th %ile ≥ 80th %ile ≤ 20th %ile ≥ 80th %ile ≤ 20th %ile ≥ 80th %ile ≤ 20th %ile ≥ 80th %ile ≤ 20th %ile ≥ 80th %ile

Lifetime use of alcohol
Initiation of use Autism Cancer Diabetes Kidney disease Epilepsy Heart condition Migraines Psychiatric ADHD/ADD Diabetes Kidney disease Migraines Autism Cancer Epilepsy Heart condition Cancer Diabetes Kidney disease Learning disab. Asthma Autism Epilepsy Migraines Cancer Heart condition Learning disab. Visual impair. Autism Hearing Impair. Kidney disease Migraines Hearing Impair. Heart condition Migraines Visual Impair. Diabetes Epilepsy Orthopedic Psychiatric
Incidence 1.8% 22.4% 17.9% 40.4% 33.7% 48.7% 54.2% 91.7% 6.8% 53.3%

Cumulative prevalence of use Autism Cancer Diabetes Kidney disease Epilepsy Heart condition Migraines Psychiatric ADHD/ADD Autism Diabetes Kidney disease Epilepsy Heart condition Hypertension Learning disab. Autism Diabetes Kidney disease Speech impair. Epilepsy Heart condition Hypertension Migraines Autism Learning disab. Speech impair. Visual impair. Epilepsy Hypertension Kidney disease Migraines Autism Hearing Impair. Speech impair. Visual impair. Cancer Hypertension Kidney disease Migraines
Prevalence 1.8% 22.4% 28.8% 40.4% 50.2% 65.7% 67.2% 81.5% 65.2% 84.2%

Binge drinking alcohol | Ever use of alcohol
Period prevalence of use Diabetes Heart condition Hypertension Visual impair. ADHD/ADD Epilepsy Migraines Orthopedic Cancer Epilepsy Kidney disease Migraines Autism Diabetes Heart condition Speech impair. Asthma Autism Kidney disease Visual impair. Diabetes Hearing Impair. Heart condition Migraines Cancer Kidney disease Orthopedic Visual impair. Autism Diabetes Epilepsy Hypertension Autism Cancer Diabetes Kidney disease Epilepsy Hearing Impair. Hypertension Speech impair.
Prevalence 0.0% 15.1% 15.2% 46.6% 26.3% 47.9% 23.6% 47.2% 7.0% 37.0%

Cumulative prevalence of use Diabetes Heart condition Hypertension Visual impair. ADHD/ADD Epilepsy Migraines Orthopedic Cancer Kidney disease Migraines Visual impair. Autism Diabetes Heart condition Speech impair. Asthma Autism Kidney disease Visual impair. Diabetes Epilepsy Hearing Impair. Learning disab. Kidney disease Migraines Orthopedic Visual impair. Autism Diabetes Hearing Impair. Hypertension Cancer Kidney disease Migraines Visual impair. Autism Diabetes Hypertension Psych condition
Prevalence 0.0% 15.1% 13.7% 36.1% 27.7% 46.8% 33.6% 54.0% 28.7% 50.0%

Lifetime use of tobacco cigarettes
Initiation of use Autism Cancer Kidney disease Migraines Epilepsy Learning disab. Other condition Psych condition Cancer Diabetes Kidney disease Orthopedic Autism Epilepsy Hypertension Psych condition Diabetes Epilepsy Heart condition Hypertension ADHD/ADD Autism Kidney disease Psych condition Autism Cancer Epilepsy Kidney disease ADHD/ADD Heart condition Migraines Speech impair. Learning disab. Orthopedic Psych condition Visual impair. Asthma Hypertension Other condition Speech impair.
Incidence 3.0% 23.4% 16.9% 37.4% 10.3% 30.2% 0.0% 9.8% 0.0% 0.6%

Cumulative prevalence of use Autism Cancer Kidney disease Migraines Epilepsy Learning disab. Other condition Psych condition Autism Cancer Kidney disease Orthopedic Epilepsy Hypertension Other condition Psych condition Autism Diabetes Kidney disease Orthopedic ADHD/ADD Hypertension Other condition Psych condition Autism Diabetes Kidney disease Orthopedic Hypertension Migraines Other condition Psych condition Autism Diabetes Kidney disease Orthopedic Hypertension Migraines Other condition Psych condition
Prevalence 3.0% 23.4% 27.2% 45.5% 37.3% 55.6% 38.4% 57.3% 38.2% 57.5%

Regular use of tobacco cigarettes | Ever use of tobacco cigarettes
Period prevalence of use Cancer Hearing Impair. Migraines Visual impair. Asthma Diabetes Other condition Psych condition Autism Hearing Impair. Heart condition Orthopedic disease Cancer Diabetes Hypertension Kidney ADHD/ADD Asthma Cancer Speech impair. Epilepsy Hearing Impair. Kidney disease Migraines Epilepsy Hearing Impair. Kidney disease Visual impair. Autism Cancer Diabetes Migraines ADHD/AD D Diabetes Heart condition Kidney disease Cancer Learning disab. Migraines Orthopedic
Prevalence 39.3% 77.4% 67.5% 94.1% 87.2% 99.1% 87.2% 100.0% 84.3% 98.1%

Cumulative prevalence of use Cancer Hearing Impair. Migraines Visual impair. Asthma Diabetes Other condition Psych condition Autism Hearing Impair. Heart condition Visual impair. Cancer Diabetes Hypertension Kidney disease Autism Heart condition Orthopedic Visual impair. Diabetes Hypertension Kidney disease Psych condition Autism Heart condition Orthopedic Visual impair. Diabetes Hypertension Kidney disease Psych condition Autism Cancer Heart condition Visual impair. Diabetes Hypertension Kidney disease Psych condition
Prevalence 39.3% 77.4% 59.6% 91.5% 69.5% 88.6% 70.2% 87.8% 68.3% 86.6%

Lifetime use of marijuana
Initiation of use Autism Cancer Kidney disease Orthopedic Heart condition Hypertension Other condition Psych condition Diabetes Kidney disease Orthopedic Visual impair. ADHD/ADD Epilepsy Hypertension Other condition Autism Hypertension Kidney disease Visual impair. Epilepsy Hearing Impair. Heart condition Learning disab. Autism Cancer Diabetes Epilepsy ADHD/ADD Heart condition Kidney disease Migraines ADHD/ADD Asthma Orthopedic Visual impair. Hypertension Migraines Psych condition Speech impair.
Incidence 10.5% 32.4% 21.1% 34.5% 2.0% 24.7% 0.0% 8.6% 0.0% 11.2%

Cumulative prevalence of use Autism Cancer Kidney disease Orthopedic Heart condition Hypertension Other condition Psych condition Autism Kidney disease Orthopedic Visual impair. Epilepsy Hypertension Other condition Psych condition Autism Kidney disease Orthopedic Visual impair. Cancer Epilepsy Hypertension Psych condition Autism Orthopedic Speech impair. Visual impair. Cancer Hypertension Other condition Psych condition Autism Orthopedic Speech impair. Visual impair. Epilepsy Hypertension Other condition Psych condition
Prevalence 10.5% 32.4% 29.4% 49.8% 35.5% 61.8% 41.1% 60.5% 41.4% 61.3%

Recent use of marijuana (without doctor recommendation) | Ever use of marijuana
Period prevalence of use Diabetes Hearing Impair. Heart condition Hypertension ADHD/ADD Epilepsy Learning disab. Orthopedic Asthma Cancer Diabetes Visual impair. Autism Heart condition Kidney disease Learning disab. Cancer Hypertension Learning disab. Migraines Heart condition Kidney disease Orthopedic Visual impair. Cancer Diabetes Heart condition Kidney disease ADHD/ADD Autism Other condition Visual impair. Cancer Diabetes Hearing Impair. Heart condition ADHD/ADD Autism Epilepsy Kidney disease
Prevalence 0.0% 11.1% 13.9% 38.1% 25.3% 46.8% 26.1% 43.4% 16.1% 53.2%

Cumulative prevalence of use Diabetes Hearing Impair. Heart condition Hypertension ADHD/ADD Epilepsy Learning disab. Orthopedic Cancer Diabetes Other condition Visual impair. Autism Epilepsy Heart condition Kidney disease Cancer Diabetes Hypertension Migraines Autism Heart condition Kidney disease Orthopedic Cancer Diabetes Hypertension Kidney disease Asthma Autism Orthopedic Psych condition Cancer Diabetes Hypertension Visual impair. Autism Heart condition Kidney disease Psych condition
Prevalence 0.0% 11.1% 10.4% 36.1% 27.5% 52.3% 40.9% 53.9% 44.7% 62.0%

a

Incidence was determined by new reporting of substance use behaviors among those who reported no use in the prior period. Values in bold represent statistically significant differences (p<0.05) comparing youth with a diagnosis of any of the listed conditions to those without.

b

Prevalence refers to the cumulative or period reporting of use behaviors among those followed through each period. Values in bold represent statistically significant differences (p<0.05) comparing youth with a diagnosis of any of the listed conditions to those without.

c

Chronic conditions include: attention deficit/hyperactivity disorder (ADHD/ADD); asthma; autism; birth defects; breathing problems; cancer; chronic hypertension; diabetes; digestive problems; emotional or psychological problems; epilepsy; heart conditions; kidney disease; learning disability or developmental delays; migraines; orthopedic conditions; sickle cell anemia; skin disease; hearing, speech, or visual impairments; and other conditions. Conditions that were too rare to yield stable estimates (i.e., birth defects, digestive problems, sickle cell anemia, and skin disease) are not shown.

d

Data are from the Panel Study of Income Dynamics, Child Development and Transition to Adulthood Supplements (2002–2011).