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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Trends Cell Biol. 2016 Feb 11;26(7):498–510. doi: 10.1016/j.tcb.2016.01.005

Figure 2. Recurrent domestication of pogo-like transposases to give rise to CENP-B DNA-binding proteins.

Figure 2

CENP-B proteins have been domesticated multiple independent times in animals and fungi. Three domesticated CENP-B-like proteins were found in fission yeast (highlighted in blue). Blue asterisks indicate potential domestications of additional CENP-B-like proteins in insects (often multiple instances per genome) predicted from bioinformatics analyses [52] that have yet to be confirmed experimentally.