Figure 3. Effects of the CB1 receptor antagonist rimonabant on responding for social play behaviour.
Treatment with rimonabant (0.1–0.3–1.0 mg/kg, n=8) reduced active responses (A) and rewards obtained (B) at the highest dose tested, did not affect inactive responses (A) and tended to reduce the breakpoint (C). The percentage of time spent scratching was increased by the two highest doses of rimonabant (D). Data is represented as mean+SEM. #0.08>p>0.05, *p<0.05, relative to vehicle (0 mg/kg rimonabant) treatment.