. Author manuscript; available in PMC: 2017 Oct 1.

Published in final edited form as: Technol Cancer Res Treat. 2015 Jul 1;15(5):651–660. doi: 10.1177/1533034615593191

Table 3.

Correlation Test Results Between Parameter Changes and Radiation Doses.

Region of interest	Parameter	Relative Change for Prescription Dose = 15 Gy	Relative Change for Prescription Dose = 18 Gy	Relative Change for Prescription Dose = 21 Gy	Pearson Coefficient r	P
PTV	rADC	0.80 ± 0.16	0.81 ± 0.11	1.25 ± 0.21	.877	.160
	iAUC_6min	1.23 ± 0.50	1.45 ± 0.40	1.87 ± 0.59	.985	.055
	K^trans	0.87 ± 0.22	1.12 ± 0.75	1.30 ± 0.33	.996	.029^a
	v_e	1.31 ± 0.61	1.56 ± 0.23	1.63 ± 0.42	.955	.096
CTV	rADC	0.79 ± 0.18	0.76 ± 0.15	1.22 ± 0.23	.834	.186
	iAUC_6min	1.25 ± 0.51	1.45 ± 0.36	1.93 ± 0.63	.974	.073
	K^trans	0.88 ± 0.23	1.41 ± 0.65	1.30 ± 0.32	.762	.224
	v_e	1.33 ± 0.61	1.43 ± 0.32	1.68 ± 0.44	.799	.073
GTV	rADC	0.58 ± 0.14	0.85 ± 0.09	1.15 ± 0.43	.999	.012^a
	iAUC_6min	0.98 ± 0.49	1.22 ± 0.20	1.18 ± 0.27	.799	.205

Abbreviations: PTV, planning target volume; CTV, clinical target volume; GTV, gross tumor volume; rADC, regional apparent diffusion coefficient; iAUC, initial area under the concentration curve.

Statistically significant (P ≤ .05) results.