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EHEC flagellin induces hBD2 and IL-8 expression in colonic biopsies. Colonic biopsies were incubated with purified flagellin (1 μg/ml) or left NI on the mucosal side for 7 h. IL-8 and hBD2 mRNA levels were quantified by qPCR and expressed as fold changes relative to matched NI controls. Data points represent individual biopsies from a total of four patients. Medians are indicated by a line. *P < 0.05, **P < 0.01 vs. NI control.
