Table 4.

Effect of S. aureus on OPG protein release by SM-HPBCs (white columns) and OM-HPBCs (gray columns).

Acute infection
OPG	1 h						3 h						6 h						9 h
pg.mL−1	Ctrl		10:1		30:1		Ctrl		10:1		30:1		Ctrl		10:1		30:1		Ctrl		10:1		30:1
Max	1705	2327	1639	3891	2053	3836	4933	8545	5813	6255	4800	8873	12,909	19,891	15,738	7227	12,773	17,636	16,133	22,065	15,147	18,370	15,413	23,043
Median	1308	1165	1128	1335	1181	1086	3365	3039	4646	2346	3268	3984	10,521	5634	10,817	6306	11,630	6654	4470	6162	5536	6401	5324	7288
Min	–	130	–	–	–	–	1000	826	1739	1522	–	2043	3565	3348	6391	4826	3565	5410	1443	3377	1902	5273	3475	4273
Persistent infection
OPG	1 h						9 h						24 h						48 h
pg.mL−1	Ctrl		10:1		30:1		Ctrl		10:1		30:1		Ctrl		10:1		30:1		Ctrl		10:1		30:1
Max	6719	6896	10,656	4938	9469	5688	17,469	12,646	10,625	10,902	11,844	9699	27,219	25,000	25,781	23,788	31,156	30,455	39,819	87,355	72,250	65,072	49,781	83,949
Median	1330	2346	1178	2529	1339	2539	4305	6915	6081	7108	5233	7253	11,548	13,958	12,679	16,361	13,515	18,292	21,231	33,149	26,050	27,990	24,734	30,538
Min	700	–	683	–	667	–	1834	155	2125	–	2334	–	4521	310	4979	143	4938	393	7875	1274	7021	1298	7083	1417

Cells were exposed to viable S. aureus (MOI of 10:1 and 30:1) for 1, 3, 6, and 9 h in acute infection and for 1, 9, 24, and 48 h in persistent infection. Data are presented as minimal value, median value, and maximal value from four independent donors (– means undetermined).