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Schematic representation of the Dnmt protein family. Shown are domain structures of mouse Dnmt proteins and the initial references. Numbers represent amino acid positions. DMAP, Dnmt1-associated protein binding domain; PBD, proliferating cell nuclear antigen (PCNA)-binding domain; TS, targeting sequence; CXXC, CXXC zinc finger domain; PBHD, polybromo-1 protein homologous domain; MTase, methyltransferase; PWWP, proline-tryptophan-tryptophan-proline motif; Cys, cysteine-rich domain.
