Table 6.
Summary of disease-related MBP alterations.
| Protein | Disease | Alteration | Reference |
|---|---|---|---|
| MECP2 | Rett syndrome | Causal MECP2 mutations of Rett syndrome are summarized in: http://mecp2.chw.edu.au/mecp2/index.php | Amir et al., 1999 |
| MBD1 | Prostate cancer | Upregulated | Patra et al., 2003 |
| MBD2 | Breast cancer | Upregulated | Billard et al., 2002 |
| MBD3 | Glioblastoma | Upregulated | Schlegel et al., 2002 |
| MBD4 | Colorectal cancer Endometrial cancer Pancreas cancer |
Frameshift mutation Frameshift mutation Frameshift mutation |
Riccio et al., 1999 |
| KAISO | Colorectal cancer | Upregulated | Lopes et al., 2008 |
| ZBTB4 | Neuroblastoma | Downregulated | Weber et al., 2008 |
| ICBP90 | Non-small-cell lung cancer | Upregulated | Daskalos et al., 2011 |
| NIRF | Lung cancer | Upregulated | He et al., 2009 |