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. 2016 Jun 21;7:115. doi: 10.3389/fgene.2016.00115

Table 6.

Summary of disease-related MBP alterations.

Protein Disease Alteration Reference
MECP2 Rett syndrome Causal MECP2 mutations of Rett syndrome are summarized in: http://mecp2.chw.edu.au/mecp2/index.php Amir et al., 1999
MBD1 Prostate cancer Upregulated Patra et al., 2003
MBD2 Breast cancer Upregulated Billard et al., 2002
MBD3 Glioblastoma Upregulated Schlegel et al., 2002
MBD4 Colorectal cancer
Endometrial cancer
Pancreas cancer
Frameshift mutation
Frameshift mutation
Frameshift mutation
Riccio et al., 1999
KAISO Colorectal cancer Upregulated Lopes et al., 2008
ZBTB4 Neuroblastoma Downregulated Weber et al., 2008
ICBP90 Non-small-cell lung cancer Upregulated Daskalos et al., 2011
NIRF Lung cancer Upregulated He et al., 2009