FIG 8.

Compound 5f did not show cytotoxic effects in vitro. (A) RBC lysis was measured in the presence of compound 5f at various concentrations (0 to 100 μM) at 2 and 12 h. (Inset) Soret spectra of supernatant of untreated RBCs and RBCs incubated with saponin/compound 5f (100 μM) at 2 and 12 h provided in the range of 300 to 700 nm. (B) The viability of HepG2 and HEK293 cells was assessed by an MTT assay of triplicate cultures, expressed as the percentage of untreated control. Data represent means ± the SD (**, P < 0.05 [versus 0 μM in HepG2 cells]; ##, P < 0.05 [versus 0 μM in HEK293 cells]).