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. 2016 Jun 20;60(7):4217–4228. doi: 10.1128/AAC.01575-15

TABLE 4.

Four-day parasite-suppressive activity of compound 5f against an MDR P. yoelii strain in mice

Compound Dose (mg/kg) Mean % ± SDa
Parasitemia Suppression
Control 58.65 ± 0.3 0
5f 10 41.91 ± 1.1* 28.48 ± 1.26
25 24.73 ± 0.8* 57.79 ± 4.43
50 11.32 ± 1.3* 80.69 ± 3.59
α/β arteether 50 0** 100
a

*, P < 0.05; **, P < 0.005 (compared to the control).