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. 2016 Jun 20;60(7):3897–3905. doi: 10.1128/AAC.00080-16

TABLE 3.

Comparison of substance-specific therapeutic indices and toxic areas

Substance therapeutic area (unit) CaSO4-G (Herafill-G) (gentamicin) CaSO4-V (vancomycin) Osteoset (tobramycin)
Total substance mass implanted (mg) 5 4.9 14.3
Therapeutic index (μg/ml) 4–12 5–40 4–8
Toxic area (μg/ml) >10–12 >80 >12