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Binding of [3H]BMS-955176 to HIV-1 Gag VLPs (A) Binding of [3H]BMS-955176 to WT HIV-1 VLP (circles, nonspecific binding to integrase subtracted) and HIV-1 integrase (control). (B) Inhibition of [3H]BMS-955176 binding to WT VLPs by nonradiolabeled BMS-955176. Results are representative of 5 experiments to determine Kd values with range of 2.3 to 6 nM.
