Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jun 2;15(11):2475–2487. doi: 10.1016/j.celrep.2016.05.020

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Epigenetic Factors Are Specifically Enriched at the V_H RSS

(A) Aligned region plot for the 2 kb centered on the RSS for V_H genes in the two active states and the V_H3609 outlier family. This shows enrichment for DHS, CTCF, and RAD21 for the A state and DHS, IRF4, and PAX5 for the E state. Enrichment is localized close to the RSS in all cases.

(B) Line graph of average relative enrichment for each factor for genes in the A and E states.

(C) Signal intensity at genome-wide Rag1-ChIP peaks. Signal intensity of five features (chosen to represent both regulatory states) and Rag2 at 3388 Rag1 peaks (Teng et al., 2015). Density defined as normalized log-based read counts in 2 kb regions centered at the summit of peaks.