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The effects of spent coffee grounds SFE on melanin content in H89 (a), Ly294002 (b), and PD98059 (c) treated B16F10 cells, respectively. The results are represented as percentages of the control, and the data are presented as the mean ± SD of three separate experiments. The values are significantly different compared with the control. ∗ p ≤ 0.05; ∗∗ p < 0.01.
