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. 2016 Jan 23;151(1):23–34. doi: 10.1093/toxsci/kfw019

FIG. 7.

FIG. 7.

Pretreatment with TUDCA (TUD; 100 μM) prevented the effects of nicotine on PERK phosphorylation and Hsd11b1 expression after 6 h in Rcho-1 TG cells. A, Specific targeted protein bands as detected by respective antibodies via Western blot. B, Protein levels of the ratio of P-PERK[Thr981]: PERK at 6 h. All arbitrary values were expressed as means normalized to Amido Black ± SEM. All experiments were performed in quadruplicates (n = 4). Significant differences between treatment groups determined by 1-way ANOVA (1WA) indicated by * (P < .05) or *** (P < .001). Different letters represent means that are significantly different from one another according to Tukey’s posttest ( P < .05).