Table 3. All integration sites in transgenic cattle.
I.D | No. | Chromosome | Insertion site | Orientation | Overlapping gene | Location | 5′ gene | 3′ gene |
---|---|---|---|---|---|---|---|---|
SNU-SB-1 | 1 | 4 | 41,232,050–41,232,051 | Reverse | GNAI1 | E1–2 intron | GNAT3 | PHTF2 |
2 | 21 | 28,416,682–28,416,683 | Forward | – | TRPM1 | APBA2 | ||
3 | 26 | 48,405,454–48,405,455 | Forward | – | MKI67 | EBF3 | ||
SNU-PB-1 | 1 | 1 | 2,651,736–2,651,737 | Reverse | – | MIS184 | HUNK | |
2 | 2 | 31,593,723–31,593,724 | Forward | – | SLC38A11 | COBLL1 | ||
3 | 3 | 54,580,493–54,580,494 | Forward | – | GBP5 | GBP4 | ||
4 | 4 | 95,433,564–95,434,563 | Forward | – | TSGA13 | MKLN1 | ||
5 | 5 | 4,588,449–4,588,450 | Reverse | – | ATXN7L3B | CAPS2 | ||
6 | 6(1) | 20,085,913–20,086,912 | Forward | – | DKK2 | GIMD1 | ||
7 | 6(2) | 99,730,977–99,731,976 | Reverse | PLAC8 | E3–E4 intron | PLAC8 | COQ2 | |
8 | 7 | 31593691 to 31593728 | Forward | – | ERAP2 | LNPEP | ||
9 | 14 | 53,149,061–53,149,062 | Reverse | – | CSMD3 | CSMD3 | ||
10 | 17 | 55,906,674–55,907,673 | Forward | KDM2B | E4-E5 intron | ORAI1 | RNF34 | |
11 | 22 | 43,933,057–43,933,058 | Forward | SLMAP | E1–2 intron | bta-mir-2370 | DENND6A | |
12 | 25 | 30,150,644–30,151,643 | Forward | – | AUTS2 | ENSBTAG00000047342 | ||
13 | 26 | 38,489,750–38,490,749 | Reverse | – | EMX2 | RAB11FIP2 | ||
14 | GJ059980.1 | 21,074–22,073 | Forward | – | – | – | ||
15 | X | 143,271,631–143,272,662 | Forward | UTY | E3-E4 intron | WWC3 | DDX3Y | |
SNU-PB-2 | 1 | 3(1) | 9,538,861–9,539,321 | Forward | ENSBTAG00000005796 | E1-E2 intron | PEX19 | PEA15 |
2 | 3(2) | 79,749,737–79,750,160 | Forward | MGC137454 | E2-E3 intron | PDE4B | OB-R | |
3 | 5(1) | 50,479,229–50,479,653 | Reverse | – | TMEM5 | AVPR1A | ||
4 | 5(2) | 55,868,825–55,869,356 | Forward | – | XRCC6BP1 | CTDSP2 | ||
5 | 5(3) | 75,829,995–75,830,420 | Reverse | – | MPST | KCTD17 | ||
6 | 6 | 40,200,341–40,200,867 | Reverse | – | LCORL | SLIT2 | ||
7 | 7 | 104,834,424–104,835,058 | Reverse | – | C7H5orf30 | NUDT12 | ||
8 | 9 | 85,788,192–85,788,618 | Forward | – | STXBP5 | SAMD5 | ||
9 | 10 | 85,854,063–85,854,558 | Forward | LIN52 | E5-E6 intron | ALDH6A1 | VSX2 | |
10 | 11(1) | 58,260,496–58,260,907 | Forward | – | PTP | LRRTM4 | ||
11 | 11(2) | 107,297,269–107,297,597 | Forward | – | PSMD13 | – | ||
12 | 15 | 36,723,446–36,723,809 | Forward | SOX6 | E3-E4 intron | SMAP | INSC | |
13 | 18 | 8,775,609–8,776,056 | Forward | MPHOSPH6 | E2-E3 intron | HSD17B2 | CDH13 | |
14 | X(1) | 91,193,469–91,194,016 | Forward | – | ARAF | SYN1 | ||
15 | X(2) | 80,581,077–80,581,395 | Forward | – | PBDC1 | MAGEE2 |