Table 1. Demographic, Anthropometrics and Hormonal Profiles of Patients With Subclinical and Overt Hypothyroidism and Euthyroid Controls a,b.
| Controls | Subclinical hypothyroidism | Overt Hypothyroidism | P Value | |
|---|---|---|---|---|
| Gender | < 0.01 | |||
| Female | 2961 (57.5) | 221 (76.7) | 83 (83) | |
| Male | 2193 (42.5) | 67 (23.3) | 17 (17) | |
| Age, y | 39.69 ± 14.23 | 38.50 ± 14.51 | 44.14 ± 13.77 | 0.003 |
| BMI, kg/m 2 | 26.34 ± 4.80 | 26.4 ± 5.04 | 28.85 ± 4.76 | 0.001 |
| Weigh, kg | 70.2 ± 12.9 | 67.7 ± 12.9 | 73.1 ± 13.6 | 0.001 |
| Waist, cm | 87.3 ± 12.0 | 85.7 ± 13.0 | 92.3 ± 11.7 | 0.001 |
| W/H ratio | 0.87 ± 0.09 | 0.87 ± 0.08 | 0.84 ± 0.09 | 0.001 |
| SBP, mmHg | 116 ± 17 | 116 ± 17 | 116 ± 18 | 0.952 |
| DBP, mmHg | 76.0 ± 10.6 | 75.2 ± 10.4 | 77.1 ± 9.5 | 0.281 |
| TSH, mU/L | 1.59 (1.37) | 6.60 (2.72) | 13.03 (29.01) | 0.001 |
| FT4, ng/dl | 1.22 ± 0.18 | 1.11 ± 0.14 | 0.72 ± 0.20 | 0.001 |
| TC, mg/dl | 200 ± 45 | 199 ± 46 | 216 ± 41 | 0.001 |
| HDLC, mg/dl | 41.7 ± 10.9 | 42 ± 11 | 42 ± 11 | 0.251 |
| LDLC, mg/dl | 127.5 ± 36 | 127.96 ± 38 | 140 ± 35 | 0.003 |
| TG, mg/dl | 133 (104) | 117 (116) | 157 (126) | 0.007 |
| TG/HDL | 4.26 ± 3.63 | 4.16 ± 4.01 | 5.06 ± 4.15 | 0.086 |
a Abbreviations: BMI, body mass index; DBP, diastolic blood pressure; FT4, free thyroxine; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, Total cholesterol; TGs, triglycerides, SBP, systolic blood pressure; TSH, thyrotropin; WC, waist circumference; W/H, waist to hip.
b All values represent mean ± SD except for TSH and TG ( median and IQR are shown).